Which factors enhance the absorption of topical water-soluble medication in premature infants?

• A. Outer layer not fully developed but is more hydrated, and wearing diapers acts as an occlusive dressing.
• B. The outer layer is fully developed and hydration status is not a factor.
• C. No particular factors influence absorption in premature infants.
• D. External warming is the primary enhancer of absorption.

Answer: (B)